Potential strategies for the management of drug resistant tuberculosis.

Clicks: 239
ID: 100753
2020
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Ranked #39 of 113 articles by views in Journal of global antimicrobial resistance

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Abstract
In the current scenario, the emergence of drug resistance in Mycobacterium tuberculosis is the consequence of the failure of conventional diagnostics and treatment approach. To combats this global emergence of drug resistance, alternative approaches such as pathogen centric (use of repurposed drugs, novel analogs of existing anti-TB drugs and novel compounds a different mechanism of action), host-centric (immunomodulatory agents, therapeutic vaccines, immune and cellular therapies) and nano-based drugs/vaccines delivery approaches should be used in single or in combination. Diverse types of nano-carriers have gauged as auspicious diagnostics and drug delivery systems. In this focused review, we have suggested a long-term solution for combating the antimicrobial resistance and also an attractive means to increase patient's compliance and reduce treatment duration.
Reference Key
sharma2020potentialjournal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sharma, Divakar;Sharma, Sandeep;Sharma, Juhi;
Journal Journal of global antimicrobial resistance
Year 2020
DOI
S2213-7165(20)30058-8
URL
Keywords
Drug resistance tuberculosis alternate strategies nano based interventions pathogen and host-centric approaches

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