The Clinical Effect of Oral Vitamin D2 Supplementation on Psoriasis: A Double-Blind, Randomized, Placebo-Controlled Study

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ID: 10010
2019
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Abstract
Background. There are limited randomized controlled trials of oral vitamin D supplementation in psoriasis, especially in Asia, and the results are inconclusive. Objective. To investigate the clinical effect of oral vitamin D supplementation on psoriasis. Methods. Patients with psoriasis were randomized to receive vitamin D2 60,000 IU or similar-looking placebo pills once every 2 weeks for 6 months. The primary outcome was improvement of the Psoriasis Area and Severity Index (PASI) score at 3 and 6 months after treatment. Serum levels of 25(OH)D, calcium, phosphate, parathyroid hormone, and C-reactive protein and adverse events were monitored. The chi-square test, Fisher’s exact test, Student’s t-test, and Spearman’s correlation analysis were used in statistical analysis. Results. Of 50 subjects screened, 45 were eligible and randomized to the oral vitamin D2 group
Reference Key
wareeporn2019thedermatology Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Disphanurat, Wareeporn;Viarasilpa, Wongsiya;Chakkavittumrong, Panlop;Pongcharoen, Padcha;Disphanurat, Wareeporn;Viarasilpa, Wongsiya;Chakkavittumrong, Panlop;Pongcharoen, Padcha;
Journal dermatology research and practice
Year 2019
DOI
10.1155/2019/5237642
URL
https://www.hindawi.com/journals/drp/2019/5237642/abs/
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