Aptamers in Education: Undergraduates Make Aptamers and Acquire 21st Century Skills Along the Way.

Clicks: 279
ID: 57541
2019
Article Quality & Performance Metrics
Overall Quality Improving Quality
0.0 /100
Combines engagement data with AI-assessed academic quality
AI Quality Assessment
Not analyzed
Abstract
Aptamers have a well-earned place in therapeutic, diagnostic, and sensor applications, and we now show that they provide an excellent foundation for education, as well. Within the context of the Freshman Research Initiative (FRI) at The University of Texas at Austin, students have used aptamer selection and development technologies in a teaching laboratory to build technical and 21st century skills appropriate for research scientists. One of the unique aspects of this course-based undergraduate research experience is that students develop and execute their own projects, taking ownership of their experience in what would otherwise be a traditional teaching lab setting. Of the many successes, this work includes the isolation and characterization of novel calf intestinal alkaline phosphatase (anti-CIAP) RNA aptamers by an undergraduate researcher. Further, preliminary survey data suggest that students who participate in the aptamer research experience express significant gains in their self-efficacy to conduct research, and their perceived ability to communicate scientific results, as well as organize and interpret data. This work describes, for the first time, the use of aptamers in an educational setting, highlights the positive student outcomes of the aptamer research experience, and presents the research findings relative to the novel anti-CIAP aptamer.
Reference Key
stovall2019aptamerssensors Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Stovall, Gwendolyn M;Huynh, Vincent;Engelman, Shelly;Ellington, Andrew D;
Journal Sensors (Basel, Switzerland)
Year 2019
DOI E3270
URL
Keywords
aptamer cure 21st century skills freshman research initiative selex systematic evolution of ligands by exponential enrichment calf-intestinal alkaline phosphatase course-based undergraduate research experience in vitro selection

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.