IL-1 receptor accessory protein is an essential component of the IL-1 receptor

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ID: 272385
1998
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Abstract
The recently described IL-1R accessory protein (IL-1R AcP) interacts with IL-1beta and the IL-1 type-IR (IL-1RI), but an essential requirement for IL-1R AcP in IL-1 signaling in vitro has not been established and its role in vivo has not been examined. In this study, IL-1R AcP-deficient mice and fib ā€¦
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Authors Cullinan EB;Kwee L;Nunes P;Shuster DJ;Ju G;McIntyre KW;Chizzonite RA;Labow MA;;
Journal Journal of immunology (Baltimore, Md. : 1950)
Year 1998
DOI DOI not found
URL
https://www.ncbi.nlm.nih.gov/pubmed/9820540
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice Inbred C57BL animals pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't female male P.H.S. cell line Fibroblasts / metabolism Receptors embryo proteins / genetics tumor necrosis factor-alpha / pharmacology inbred strains gene targeting mammalian gene expression regulation / immunology binding interleukin-1 / genetics interleukin-6 / biosynthesis proteins / physiology* interleukin-1 / pharmacology interleukin-1 / physiology* pmid:9820540 e b cullinan l kwee m a labow competitive / immunology interleukin-1 receptor accessory protein stem cells

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