inhibition of the lipid oxidation processes by the kazakhstani-soil endemic plants

Abstract

Phospholipids (PL) are universal components of cell membranes. They can be used as objective indices of normal or pathological organism states. The changing nature of the quantitative composition of PL is indicating the intensity of oxidative stress as well as the efficiency of exogenous plant antioxidants.The PL dynamics of the ischemia in experimental rat’s was investigated. The change of that parameter using the preventive injection of some vegetation organs of Kazakhstan birch extract.The extracts of the birch vegetation organs in experimental group were dosed in the amount of 5 mg/kg. In order to investigate PL dynamics, the tissues of brain, liver, and kidney have been studied.In order to estimate the PL change range in rat homogenate, the correlation between neutral and acid PL. Despite the fact that the amount of acid PL in the bio-membranes is less than the neutral ones, the latter regulate membrane functions in a higher degree.It has been found that the rats which had experienced ischemia have a decreased amount of acid PL in the homogenates. Preventive injection of birch extracts brings about normalization of PL level. This fact points out a possibility of applying extracts of Betula Pendula Roth in order to regulate the PL level of experimental rats as well as an estimation of the antioxidant effect of exogenoussubstances.