eosinophils reduce chronic inflammation in adipose tissue by secreting th2 cytokines and promoting m2 macrophages polarization
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2015
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Abstract
Obesity is now recognized as a low-grade, chronic inflammatory disease that is linked to a myriad of disorders including cardiovascular diseases, type 2 diabetes, and liver diseases. Recently it is found that eosinophils accelerate alternative activation macrophage (AAM) polarization by secreting Th2 type cytokines such as interleukin-4 and interleukin-13, thereby reducing metainflammation in adipose tissue. In this review, we focused on the role of eosinophils in regulating metabolic homeostasis and obesity.| Reference Key |
zhang2015internationaleosinophils
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| Authors | ;Yi Zhang;Peng Yang;Ran Cui;Manna Zhang;Hong Li;Chunhua Qian;Chunjun Sheng;Shen Qu;Le Bu |
| Journal | zhonghua wei zhong bing ji jiu yi xue |
| Year | 2015 |
| DOI | 10.1155/2015/565760 |
| URL | |
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