PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro

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ID: 110724
1999
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Abstract
The process of adipogenesis is known to involve the interplay of several transcription factors. Activation of one of these factors, the nuclear hormone receptor PPAR gamma, is known to promote fat cell differentiation in vitro. Whether PPAR gamma is required for this process in vivo has remained an ā€¦
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Authors Rosen ED;Sarraf P;Troy AE;Bradwin G;Moore K;Milstone DS;Spiegelman BM;Mortensen RM;;
Journal molecular cell
Year 1999
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/10549292
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice RNA animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't female male P.H.S. Receptors Chimera Knockout pmid:10549292 doi:10.1016/s1097-2765(00)80211-7 e d rosen p sarraf r m mortensen adipose tissue / growth & development* cell differentiation / genetics* gene dosage gene targeting / methods glucose / metabolism in situ hybridization antisense messenger / metabolism cytoplasmic and nuclear / genetics* cytoplasmic and nuclear / metabolism sebaceous glands / cytology skin / cytology stem cells / metabolism transcription factors / genetics* transcription factors / metabolism

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