Bacteria-nanoparticle interactions in the context of nanofouling.

Abstract

The attachment of microbial communities to surfaces is a well-known problem recognized to be involved in a variety of critical issues in the sectors of food processing, chronic wounds, infection from implants, clogging of membranes and corrosion of equipment. Considering the importance of the detrimental impact of biofouling, it has received much attention in the scientific community and from concerned stakeholders. With the development of nanotechnology and the nowadays widespread use of engineered nanoparticles (ENPs), concerns have been raised regarding their fate in terrestrial and aquatic environments. Safety aspects and public health issues are critical in the management of handling nanomaterials and their nanowastes. The interactions of various types of nanoparticles (NPs) with planktonic bacteria have also received attention due to their antimicrobial properties. However, their behavior in regard to biofilms is not well understood although, in the environment, most of the bacteria prefer living in sessile communities. The question appears relevant considering the need to build knowledge on the fate of nanoparticles and the fact that no one can exclude the risk of accumulation of nanoparticles in biofilms and on surfaces leading to a form of nanofouling involving both engineered nanoparticles (ENPs) and nanoplastics. The present analysis of recent research accounts allows in identifying that (1) research activities related to water remediation systems have been mostly oriented on the impact of NPs on pre-existing biofilms, (2) experimental designs are restricted to few scenarios of exposure, usually limited to relative short-time periods although nanofouling could favour the development of multi-resistant bacterial species through sub-lethal exposures over prolong periods of time (3) nanofouling in other systems in which biofilms develop remains to be addressed, and (4) new research directions are required for investigating the mechanisms involved and the subsequent impact of nanofouling on bacterial consortium responses encountered in a variety of environments such as those prevailing in food production/processing settings. Finally, this review aims at providing recent information and insights on nanoparticle-bacterial interactions in the context of biofilms in order to supply an updated outlook of research perspectives that could help establish the framework for production, use and fate of nanomaterials as well as future research directions.