Plant Extracts Loaded in Nanostructured Drug Delivery Systems for Treating Parasitic and Antimicrobial Diseases.

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ID: 76881
2019
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Abstract
Plant extracts loaded in nanostructured drug delivery systems (NDDSs) have been reported as an alternative to current therapies for treating parasitic and antimicrobial diseases. Among their advantages, plant extracts in NDSSs increase the stability of the drugs against environmental factors by promoting protection against oxygen, humidity, and light, among other factors; improve the solubility of hydrophobic compounds; enhance the low absorption of the active components of the extracts (i.e., biopharmaceutical classification II), which results in greater bioavailability; and control the release rate of the substances, which is fundamental to improving the therapeutic effectiveness. In this review, we present the most recent data on NDDSs using plant extracts and report results obtained from studies related to in vitro and in vivo biological activities.
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gondim2019plantcurrent Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Gondim, Brenna L C;Oshiro-Júnior, João A;Fernanandes, Felipe H A;Nóbrega, Fernanda P;Castellano, Lúcio R C;Medeiros, Ana C D;
Journal current pharmaceutical design
Year 2019
DOI 10.2174/1381612825666190628153755
URL
Keywords
in vitro environmental factors parasitic and antimicrobial resistance in vivo nanostructured drug delivery systems plant extracts.

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