The PI3KCA and AKT Inhibitory Activities of Lour. Fruits and Heartwoods Towards Hela Cells.

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2019
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Abstract
To investigated the activities of chloroform fractions at pH 7 of Lour. Fruits and heartwoods (CF-7F and CF-7H) in decrease expression of PI3KCA, Akt-1 and Akt-2 genes towards cervical cancer cell culture (HeLa) experiments in vitro.CF-7F and CF-7H (12.5 and 25 Āµg/mL) were tested for its potential inhibition on gene expression of and genes by Reverse Transcription-Polymerase Chain Reaction (RT-PCR) method.CF-7F and CF-7H were showed the activity to reduce the expression of and genes.Our results suggest that CF-7F and CF-7H significantly inhibit the expression of and genes.
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dalimunthe2019theopen Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Dalimunthe, Aminah;Hasibuan, Poppy Anjelisa Zaitun;Satria, Denny;
Journal open access macedonian journal of medical sciences
Year 2019
DOI 10.3889/oamjms.2019.317
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Keywords
fruits akt heartwoods litsea cubeba lour pi3kca

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