Synthesis of Pharmaceutical Polyhydroquinolines Cat alyzed by Cobalt (II) Complex as Reusable Catalyst
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ID: 74104
2018
Polyhydroquinolines have been synthesized efficiently using a novel Co(II) complex based on5-nitro-N1-((pyridin- 2-yl)methylene)benzene-1,2-diamine(CoL2). This green catalyst has been utilized in a one-pot four-component Hantzsch condensation of dimedone, aldehydes, ethyl acetoacetate and ammonium acetate under solvent and free-solvent conditions. This method offers several advantages such as easy isolation of product, environmentally benign and excellent yields.
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| Authors | Pakdaman, Fahimeh;Allameh, Sadegh;Shake, Mohammad; |
| Journal | journal of research in medical and dental science |
| Year | 2018 |
| DOI | DOI not found |
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