Electrospun core-shell nanofibers as an adsorbent for on-line micro-solid phase extraction of monohydroxy derivatives of polycyclic aromatic hydrocarbons from human urine, and their quantitation by LC-MS.
Clicks: 274
ID: 71352
2019
A method is described for automatted on-line micro-solid phase extraction using polydopamine-modified polystyrene/silica electrospun nanofibers as an adsorbent for monohydroxy metabolites of polycyclic aromatic hydrocarbons (OH-PAHs). They were then quantified by liquid chromatography-mass spectrometry. The sorbent has a network structure, high porosity, stability, hydrophilicity and good extraction capacity. Under optimal experimental conditions, the method has (a) wide linear ranges (0.03-25 ng·mL for 3-hydroxyphenanthrene and 1-hydroxypyrene; and 0.05-25 ng·mL for 2-naphthol), (b) good precision (with relative standard deviations from 2.0 to 12.4%), (c) high enrichment factors (24-112), (d) low limits of detection (2-21 pg·mL), and (e) acceptable recoveries from spiked samples (79.1 to 108%). The method was successfully applied for the analysis of trace OH-PAHs in urine. Graphical abstractSchematic illustration of online micro-solid phase extraction using polydopamine-modified polystyrene/silica electrospun nanofibers as adsorbent for the enrichment and determination of monohydroxy metabolites of polycyclic aromatic hydrocarbons (OH-PAHs) prior to LC-MS analysis.
| Reference Key |
chen2019electrospunmikrochimica
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Chen, Dan;Xu, Hui; |
| Journal | Mikrochimica acta |
| Year | 2019 |
| DOI | 10.1007/s00604-019-4007-3 |
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.