Is whole-culture synchronization biology's 'perpetual-motion machine'?

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2004
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Abstract
Whole-culture or batch synchronization cannot, in theory, produce a synchronized culture because it violates a fundamental law that proposes that no batch treatment can alter the cell-age order of a culture. In analogy with the history of perpetual-motion machines, it is suggested that the study of these whole-culture 'synchronization' methods might lead to an understanding of general biological principles even though these methods cannot be used to study the normal cell cycle.
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Authors Cooper, Stephen;
Journal Trends in Biotechnology
Year 2004
DOI 10.1016/j.tibtech.2004.04.009
URL
Keywords
tolerance suppression effector regulation negative selection self-nonself discrimination

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