SASOP Biological Psychiatry Congress 2013 Abstracts

List of abstracts and authors: 1. Bipolar disorder not otherwise specified -overdiagnosed or underdiagnosed? E Allers 2. The prognosis of major depression untreated and treated: Does the data reflect the true picture of the prognosis of this very common disorder? E Allers 3. Can we prolong our patients' life expectancy? Providing a better quality of life for patients with severe mental illness O A Betencourt 4. The scope of ECT practice in South Africa J Benson-Martin, P Milligan 5. Biomarkers for schizophrenia: Can we evolve like cancer therapeutics? P Buckley 6. Relapse in schizophrenis: Major challenges in prediction and prevention P Buckley 7. Informed consent in biological treatments: The right to know the duty to inform I Chetty 8. Effectiveness of a long-acting injectable antipsychotic plus an assertive monitoring programme in first-episode schizophrenia B Chiliza, L Asmal, O Esan, A Ojagbemi, O Gureje, R Emsley 9. Name, shame, fame P Cilliers 10. Can we manage the increasing incidence of violent raging children? We have to! H Clark 11. Serotonin, depression and antidepressant action P Cowen 12. Prevalence and correlates of comorbid psychiatris illness in patients with heroin use disorder admitted to Stikland Opioid Detoxification Unit L Dannatt, K J Cloete, M Kidd, L Weich 13. Investigating the association between diabetes mellitus, depression and psychological distress in a cohort of South African teachers A K Domingo, S Seedat, T M Esterhuizen, C Laurence, J Volmink, L Asmal 14. Neuropeptide S -emerging evidence for a role in anxiety K Domschke 15. Pathogenetics of anxiety K Domschke 16. The effects of HIV on the fronto-striatal system S du Plessis, M Vink, J Joska, E Koutsilieri, C Scheller, B Spottiswoode, D Stein, R Emsley 17. Effects of acute antipsychotic treatment on brain morphology in schizophrenia R Emsley, L Asmal, B Chiliza, S du Plessis, J Carr, A Goosen, M Kidd, M Vink, R Kahn 18. Development of a genetic database resource for monitoring of breast cancer patients at risk of physical and psychological complications K Grant, F J Cronje, K Botha, J P Apffelstaedt, M J Kotze 19. Unipolar mania reconsidered: Evidence from a South African study C Grobler 20. Antipsychotic-induced movement disorders: Occurence and management P Haddad 21. The place of observational studies in assessing the effectiveness of long-acting injectable antipsychotics P Haddad 22. Molecular mechanisms of d-cycloserine in fear extinction: Insights from RNS sequencing S Hemmings, S Malan-Muller, L Fairbairn, M Jalali, E J Oakeley, J Gamieldien, M Kidd, S Seedat 23. Schizophrenia: The role of inflammation DC Henderson 24. Addictions: Emergent trends and innovations V Hitzeroth 25. The socio-cultural-religious context of biological psychiatric practice B Janse van Rensburg 26. Biochemical markers for identifying risk factors for disability progression in multiple sclerosis S Janse van Rensburg, M J Kotze, F J Cronje, W Davis, K Moremi, M Jalali Sefid Dashti, J Gamieldien, D Geiger, M Rensburg, R van Toorn, M J de Klerk, G M Hon, T Matsha, S Hassan, R T Erasmus 27. Alcohol-induced psychotic disorder: Brain perfusion and psychopathology - before and after antipsychotic treatment G Jordaan, J M Warwick, D G Nel, R Hewlett, R Emsley 28.'Pump and dump': Harm reduction strategies for breastfeeding while using substances L Kramer 29. Adolescent neuropsychiatry - an emerging field in South African adolescent psychiatric services A Lachman 30. Recovery versus remission, or what it means to be healthy for a psychiatric patient? B Latecki 31. Holistic methods utilised to normalise behaviours in youth diagnosed with neuro-biochemical disorders P Macqueen 32. Candidate genes and novel polymorphisms for anxiety disorder in a South African cohort N McGregor, J Dimatelis, S M J Hemmings, C J Kinnear, D Stein, V Russel, C Lochner 33. Higher visual functioning A Moodley 34. The effects of prenatal methylmercury exposure on trace element and antioxidant levels in rat offspring following 6-hydroxydopamine-induced neuronal insult Z M Moosa, W M U Daniels, M V Mabandla 35. Paediatric neuropsychiatric movement disorders L Mubaiwa 36. The South African national female offenders study M Nagdee, L Artz, C de Clercq, P de Wet, H Erlacher, S Kaliski, C Kotze, L Kowalski, J Naidoo, S Naidoo, J Pretorius, M Roffey, F Sokudela, U Subramaney 37. Neurobiological consequences of child abuse C Nemeroff 38. What do Stellenbosch Unviversity medical students think about psychiatry - and why should we care? G Nortje, S Suliman, K Seed, G Lydall, S Seedat 39. Neurological soft skins in Nigerian Africans with first episode schizophrenia: Factor structure and clinical correlates A Ojagbemi, O Esan, O Gureje, R Emsley 40. Should psychiatric patients know their MTHFR status? E Peter 41. Clinical and functional outcome of treatment refractory first-episode schizophrenia L Phahladira, R Emsley, L Asmal, B Chiliza 42. Bioethics by case discussion W Pienaar 43. Reviewing our social contract pertaining to psychiatric research in children, research in developing countries and distributive justice in pharmacy W Pienaar 44. The performance of the MMSE in a heterogenous elderly South African population S Ramlall, J Chipps, A I Bhigjee, B J Pillay 45. Biological basis addiction (alocohol and drug addiction) S Rataemane 46. Volumetric brain changes in prenatal methamphetamine-exposed children compared with healthy unexposed controls A Roos, K Donald, G Jones, D J Stein 47. Single voxel proton magnetic resonance spectroscopy of the amygdala in social anxiety disorder in the context of early developmental trauma D Rosenstein, A Hess, S Seedat, E Meintjies 48. Discussion of HDAC inhibitors, with specific reference to supliride and its use during breastfeeding J Roux 49. Prevalence and clinical correlates of police contact prior to a first diagnosis of schizophrenia C Schumann, L Asmal, K Cloete, B Chiliza, R Emsley 50. Are dreams meaningless? M Solms 51. The conscious id M Solms 52. Depression and resilience in HIV-infected women with early life stress: Does trauma play a mediating role? G Spies, S Seedat 53. State of affairs analysis for forensic psychiatry in SA U Subramaney 54. Escitalopram in the prevention of post-traumatic stress disorder: A pilot randomised controlled trial S Suliman, S Seedat, J Pingo, T Sutherland, J Zohar, D J Stein 55. Epigenetic consequences of adverse early social experiences in primates S Suomi 56. Risk, resilience, and gene x environment interactions in primates S Suomi 57. Biological aspects of anorexia nervosa C Szabo 58. Agents used and profiles of non-fatal suicidal behaviour in East London H Uys 59. The contributions of G-protein coupled receptor signalling to opioid dependence J van Tonder 60. Emerging trend and innovation in PTSD and OCD J Zohar 61. Making the SASOP treatment guidelines operational E Allers Poster Presentations 62. Neuropsychological deficits in social anxiety disorder in the context of early developmental trauma S Bakelaar, D Rosenstein, S Seedat 63.Social anxiety disorder in patients with or without early childhood trauma: Relationship to behavioral inhibition and activation and quality of life S Bakelaar, C Bruijnen, A Sambeth, S Seedat 64. Exploring altered affective processing in obssessive compulsive disorder symptom subtypes E Breet, J Ipser, D Stein, C Lochner 65. To investigate the bias toward recognising the facial expression of disgust in obsessive compulsive disorder as well as the effect of escitalopram E Breet, J Ipser, D Stein, C Lochner 66. A fatal-case of nevirapine-induced Stevens-Johnson's syndrome in HIV mania A Bronkhorst, Z Zingela, W M Qwesha, B P Magigaba 67. Association of the COMT G472A (met/met) genotype with lower disability in people diagnosed with multiple sclerosis W Davis, S J van Rensburg, L Fisher, F J Cronje, D Geiger, M J Kotze 68. Homocycsteine levels are associated with the fat mass and obesity associated gene FTO(intron 1 T>A) polymorphism in MS patients W Davis, S J Van Rensburg, M J Kotze, L Fisher, M Jalali, F J Cronje, K Moremi, J Gamieldien, D Geiger, M Rensburg, R van Toorn, M J de Klerk, G M Hon, T Matsha, S Hassan, R T Erasmus 69. Analysis of the COMT 472 G>A (rs4680) polymorphism in relation to environmental influences as contributing factors in patients with schizophrenia D de Klerk, S J van Rensburg, R A Emsley, D Geiger, M Rensburg, R T Erasmus, M J Kotze 70. Dietary folate intake, homocysteine levels and MTHFR mutation detection in South African patients with depression: Test development for clinical application D Delport, N vand der Merwe, R Schoeman, M J Kotze 71. The use ofexome sequencing for antipsychotic pharmacogenomic applications in South African schizophrenia patients B Drogmoller, D Niehaus, G Wright, B Chiliza, L Asmal, R Emsley, L Warnich 72. The effects of HIV on the ventral-striatal reward system S du Plessis, M Vink, J Joska, E Koutsilieri, C Scheller, B Spottiswoode, D Stein, R Emsley 73. Xenomelia relates to asymmetrical insular activity: A case study of fMRI S du Plessis, M Vink, L Asmal 74. Maternal mental helath: A prospective naturalistic study of the outcome of pregancy in women with major psychiatric disorders in an African country E du Toit, L Koen, D Niehaus, B Vythilingum, E Jordaan, J Leppanen 75. Prefrontal cortical thinning and subcortical volume decrease in HIV-positive children with encephalopathy J P Fouche, B Spottiswoode, K Donald, D Stein, J Hoare 76. H-magnetic resonance spectroscopy metabolites in schizophrenia F Howells, J Hsieh, H Temmingh, D J Stein 77. Hypothesis for the development of persistent methamphetamine-induced psychosis J Hsieh, D J Stein, F M Howells 78. Culture, religion, spirituality and psychiatric practice: The SASOP Spirituality and Psychiatry Special Interest Group Action Plan for 2012-2014 B Janse van Rensburg 79. Cocaine reduces the efficiency of dopamine uptake in a rodent model of attention-deficit/hyperactivity disorder: An in vivo electrochemical study L Kellaway, J S Womersley, D J Stein, G A Gerhardt, V A Russell 80. Kleine-Levin syndrome: Case in an adolescent psychiatric unit A Lachman 81. Increased inflammatory stress specific clinical, lifestyle and therapeutic variables in patients receiving treatment for stress, anxiety or depressive symptoms H Luckhoff, M Kotze, S Janse van Rensburg, D Geiger 82. Catatonia: An eight-case series report M Mabenge, Z Zingela, S van Wyk 83. Relationship between anxiety sensitivity and childhood trauma in a random sample of adolescents from secondary schools in Cape Town L Martin, M Viljoen, S Seedat 84. 'Making ethics real'. An overview of an ethics course presented by Fraser Health Ethics Services, BC, Canada JJ McCallaghan 85. Clozapine discontinuation rates in a public healthcare setting M Moolman, W Esterhuysen, R Joubert, J C Lamprecht, M S Lubbe 86. Retrospective review of clozapine monitoring in a publica sector psychiatric hospital and associated clinics M Moolman, W Esterhuysen, R Joubert, J C Lamprecht, M S Lubbe 87. Association of an iron-related TMPRSS6 genetic variant c.2007 C>7 (rs855791) with functional iron deficiency and its effect on multiple sclerosis risk in the South African population K Moremi, S J van Rensburg, L R Fisher, W Davis, F J Cronje, M Jalali Sefid Dashti, J Gamieldien, D Geiger, M Rensburg, R van Toorn, M J de Klerk, G M Hon, T Matsha, S Hassan, R T Erasmus, M Kidd, M J Kotze 88. Identifying molecular mechanisms of apormophine-induced addictive behaviours Z Ndlazi, W Daniels, M Mabandla 89. Effects of lifestyle factors and biochemistry on the major neck blood vessels in patients with mutiple sclerosis M Nelson, S J van Rensburg, M J Kotze, F Isaacs, S Hassan 90. Nicotine protects against dopamine neurodegenration and improves motor deficits in a Parkinsonian rat model N Ngema, P Ngema, M Mabandla, W Daniels 91. Cognition: Probing anatomical substrates H Nowbath 92. Chronic exposure to light reverses the effects of maternal separation on the rat prefrontal cortex V Russel, J Dimatelis 93. Evaluating a new drug to combat Alzheimer's disease S Sibiya, W M U Daniels, M V Mabandla 94. Structural brain changes in HIV-infected women with and without childhood trauma G Spies, F Ahmed, C Fennema-Notestine, S Archibald, S Seedat 95. Nicotine-stimulated release of hippocampal norepinephrine is reduced in an animal model of attention-deficit/ hyperactivity disorder: the spontaneously hypertensive rat T Sterley 96. Brain-derive neurotrophic factor (BDNF) protein levels in anxiety disorders: Systematic review and meta-regression analysis S Suliman, S M J Hemmings, S Seedat 97. A 12-month retrospective audit of the demographic and clinical profile of mental healthcare users admitted to a district level hospital in the Western Cape, South Africa E Thomas, K J Cloete, M Kidd, H Lategan 98. Magnesium recurarization: A comparison between reversal of neuromuscular block with sugammadex v. neostigmine/ glycopyrrolate in an in vivo rat model M van den Berg, M F M James, L A Kellaway 99. Identification of breast cancer patients at increased risk of 'chemobrain': Case study and review of the literature N van der Merwe, R Pienaar, S J van Rensburg, J Bezuidenhout, M J Kotze 100. The protective role of HAART and NAZA in HIV Tat protein-induced hippocampal cell death S Zulu, W M U Daniels, M V Mabandla