Recent advances in graphene-based nanomaterials: properties, toxicity and applications in chemistry, biology and medicine.

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2019
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Abstract
This review (with 239 refs.) summarizes the progress that has been made in applications of graphene-based nanomaterials (such as plain graphene, graphene oxides, doped graphene oxides, graphene quantums dots) in biosensing, imaging, drug delivery and diagnosis. Following an introduction into the field, a first large section covers the toxicity of graphene and its derivatives (with subsections on bacterial toxicity and tissue toxicity). The use of graphene-based nanomaterials in sensors is reviewed next, with subsections on electrochemical, FET-based, fluorescent, chemiluminescent and colorimetric sensors and probes. The large field of imaging is treated next, with subchapters on optical, PET-based, and magnetic resonance based methods. A concluding section summarizes the current status, addresses current challenges, and gives an outlook on potential future trends. Graphical Abstract Schematic presentation of the potential applications of graphene-based materials in life science and biomedicine, emphatically reflected in some vital areas such as DNA analysis, biological monitoring, drug delivery, in vitro labelling, in vivo imaging, tumor target, etc.
Reference Key
yao2019recentmikrochimica Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yao, Jun;Wang, Heng;Chen, Min;Yang, Mei;
Journal Mikrochimica acta
Year 2019
DOI 10.1007/s00604-019-3458-x
URL
Keywords
cancer therapy fluorescence imaging sensors colorimetry electrochemistry chemiluminescence disease diagnosis field-effect transistor graphene derivatives

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