Evalution of the castrated male Sprague-Dawley rat as a model of the metabolic syndrome and type 2 diabetes
Clicks: 239
ID: 274755
2006
Compared to humans rats respond differently to testosterone deficiency. Only few of the features typical for the human metabolic syndrome were observed in castrated male Sprague-Dawley rats. Therefore, we conclude that with the present experimental setup the castrated rat is not an optimal model for …
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b2006internationalevalution
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| Authors | Christoffersen B;Raun K;Svendsen O;Fledelius C;Golozoubova V;; |
| Journal | international journal of obesity (2005) |
| Year | 2006 |
| DOI | DOI not found |
| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
male
Disease Models
animal*
Rats
Sprague-Dawley
Random Allocation
body composition / physiology
Blood Glucose / metabolism
adipose tissue / metabolism
diabetes mellitus
area under curve
testosterone / blood*
type 2 / blood
testosterone / deficiency
type 2 / epidemiology
type 2 / etiology*
pmid:16505834
doi:10.1038/sj.ijo.0803261
b christoffersen
k raun
v golozoubova
metabolic syndrome / blood
metabolic syndrome / epidemiology
metabolic syndrome / etiology*
orchiectomy*
|
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