Ectopic expression of the nude gene induces hyperproliferation and defects in differentiation: implications for the self-renewal of cutaneous epithelia

Clicks: 233
ID: 274600
1999
Nude mice are characterized by the absence of visible hair, epidermal defects, and the failure to develop a thymus. This phenotype results from loss-of-function mutations in Whn (Hfh11), a winged-helix transcription factor. In murine epidermis and hair follicles, endogenous whn expression is induced …
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dm1999developmentalectopic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Prowse DM;Lee D;Weiner L;Jiang N;Magro CM;Baden HP;Brissette JL;;
Journal Developmental biology
Year 1999
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