Reconstitution of mitotic chromatids with a minimum set of purified factors

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ID: 274472
2015
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Abstract
The assembly of mitotic chromosomes, each composed of a pair of rod-shaped chromatids, is an essential prerequisite for accurate transmission of the genome during cell division. It remains poorly understood, however, how this fundamental process might be achieved and regulated in the cell. Here we r ā€¦
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Authors Shintomi K;Takahashi TS;Hirano T;;
Journal Nature Cell Biology
Year 2015
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/26075356
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't male hela cells transfection phosphorylation dna-binding proteins / metabolism dna topoisomerases xenopus proteins / genetics mitosis* adenosine triphosphatases / metabolism type ii / metabolism multiprotein complexes / metabolism saccharomyces cerevisiae proteins / genetics xenopus laevis saccharomyces cerevisiae proteins / metabolism* chromatin assembly and disassembly* xenopus proteins / metabolism* histones / metabolism* nucleosomes / enzymology saccharomyces cerevisiae tatsuya hirano cdc2 protein kinase / metabolism pmid:26075356 doi:10.1038/ncb3187 keishi shintomi tatsuro s takahashi chromatids / enzymology* high mobility group proteins / metabolism histones / genetics molecular chaperones / genetics molecular chaperones / metabolism* nucleoplasmins / metabolism spermatozoa / enzymology* transcriptional elongation factors / metabolism

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