Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons

Clicks: 371
ID: 274239
2010
Article Quality & Performance Metrics
Overall Quality Improving Quality
0.0 /100
Combines engagement data with AI-assessed academic quality
AI Quality Assessment
Not analyzed
Abstract
Circulating ghrelin is decreased in obesity, and peripheral ghrelin does not induce food intake in obese mice. We investigated whether ghrelin resistance was a centrally mediated phenomenon involving dysregulated neuropeptide Y (NPY) and agouti-related peptide (AgRP) circuits. We show that diet-indu ā€¦
Reference Key
di2010endocrinologydiet-induced Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Briggs DI;Enriori PJ;Lemus MB;Cowley MA;Andrews ZB;;
Journal endocrinology
Year 2010
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/20826561
Keywords
diet National Center for Biotechnology Information NCBI NLM MEDLINE Mice Inbred C57BL animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't male cognition / drug effects neurons / metabolism obesity / complications obesity / blood obesity / metabolism* eating / physiology eating / drug effects neuropeptide y / metabolism* obese goats growth hormone / metabolism zane b andrews agouti-related protein / metabolism* ghrelin / genetics ghrelin / metabolism* ghrelin / pharmacology pmid:20826561 doi:10.1210/en.2010-0556 dana i briggs pablo j enriori arcuate nucleus of hypothalamus / metabolism* cognition / physiology atherogenic drug resistance* / physiology ghrelin / blood obesity / etiology

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.