Adaptor-mediated recruitment of RNA polymerase II to a signal-dependent activator

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ID: 274147
1996
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Abstract
The second messenger cAMP stimulates the expression of a number of target genes via the protein kinase A-mediated phosphorylation of CREB at Ser-133 (Gonzalez, G. A., and Montminy, M. R. (1989) Cell 59, 675-680). Ser-133 phosphorylation enhances CREB activity by promoting interaction with a 265-kDa …
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Authors Kee BL;Arias J;Montminy MR;;
Journal The Journal of biological chemistry
Year 1996
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