Mechanism of action of T-705 against influenza virus
Clicks: 194
ID: 273113
2005
T-705, a substituted pyrazine compound, has been found to exhibit potent anti-influenza virus activity in vitro and in vivo. In a time-of-addition study, it was indicated that T-705 targeted an early to middle stage of the viral replication cycle but had no effect on the adsorption or release stage. …
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y2005antimicrobialmechanism
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| Authors | Furuta Y;Takahashi K;Kuno-Maekawa M;Sangawa H;Uehara S;Kozaki K;Nomura N;Egawa H;Shiraki K;; |
| Journal | Antimicrobial agents and chemotherapy |
| Year | 2005 |
| DOI | DOI not found |
| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
pubmed abstract
nih
national institutes of health
national library of medicine
chromatography
antiviral agents / pharmacology*
rna / biosynthesis
high pressure liquid
orthomyxoviridae / drug effects*
yousuke furuta
amides / pharmacology*
pyrazines / pharmacology*
pmid:15728892
pmc549233
doi:10.1128/aac.49.3.981-986.2005
kazumi takahashi
kimiyasu shiraki
dna / biosynthesis
dna-directed rna polymerases / antagonists & inhibitors
imp dehydrogenase / antagonists & inhibitors
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