Crystal structure of a naturally occurring dinucleoside phosphate: Uridylyl 3′,5′-adenosine phosphate model for RNA chain folding
Clicks: 161
ID: 272730
1972
Article Quality & Performance Metrics
Overall Quality
Improving Quality
0.0
/100
Combines engagement data with AI-assessed academic quality
Reader Engagement
Emerging Content
0.3
/100
1 views
1 readers
Trending
AI Quality Assessment
Not analyzed
The crystal structure of uridylyl 3′,5′-adenosine phosphate (UpA) has been determined and refined to an R value of 0.062. There are two UpA molecules per asymmetric unit in a monoclinic unit cell with dimensions a = 16.91, b = 12.37, c = 11.25 Å and β = 96.0 °. The conformation of the phosphodiester linkage is different for the two molecules; one UpA suggests a model for a sharp turn in a single-stranded nucleic acid structure and the other for a helical structure. All the nucleoside units have similar conformations. There is no complementary base pairing between the adenines and uracils but rather layers of base-paired adenines and base-paired uracils separated by 3.4 Å. The predominant form of base stacking involves the ribosyl oxygen atom and the bases.
| Reference Key |
berman1972journalcrystal
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Joel L. Sussman,Nadrian C. Seeman,S.-H. Kim,Helen M. Berman;Joel L. Sussman;Nadrian C. Seeman;S.-H. Kim;Helen M. Berman; |
| Journal | Journal of molecular biology |
| Year | 1972 |
| DOI | 10.1016/0022-2836(72)90423-8 |
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.