Evidence that microRNAs are associated with translating messenger RNAs in human cells - Nature Structural & Molecular Biology
Clicks: 179
ID: 271989
2006
Article Quality & Performance Metrics
Overall Quality
Improving Quality
0.0
/100
Combines engagement data with AI-assessed academic quality
Reader Engagement
Emerging Content
0.3
/100
1 views
1 readers
Trending
AI Quality Assessment
Not analyzed
MicroRNAs (miRNAs) regulate gene expression post-transcriptionally by binding the 3ā² untranslated regions of target mRNAs. We examined the subcellular distribution of three miRNAs in exponentially growing HeLa cells and found that the vast majority are associated with mRNAs in polysomes. Several lines of evidence indicate that most of these mRNAs, including a known miRNA-regulated target (KRAS mRNA), are actively being translated.
| Reference Key |
a2006natureevidence
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Maroney, Patricia A;Yu, Yang;Fisher, Jesse;Nilsen, Timothy W;Maroney, Patricia A;Yu, Yang;Fisher, Jesse;Nilsen, Timothy W; |
| Journal | Nature structural & molecular biology |
| Year | 2006 |
| DOI | doi:10.1038/nsmb1174 |
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.