Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays
Clicks: 272
ID: 271879
2010
Genome sequencing of large numbers of individuals promises to advance the understanding, treatment, and prevention of human diseases, among other applications. We describe a genome sequencing platform that achieves efficient imaging and low reagent consumption with combinatorial probe anchor ligatio …
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r2010sciencehuman
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| Authors | Drmanac R;Sparks AB;Callow MJ;Halpern AL;Burns NL;Kermani BG;Carnevali P;Nazarenko I;Nilsen GB;Yeung G;Dahl F;Fernandez A;Staker B;Pant KP;Baccash J;Borcherding AP;Brownley A;Cedeno R;Chen L;Chernikoff D;Cheung A;Chirita R;Curson B;Ebert JC;Hacker CR;Hartlage R;Hauser B;Huang S;Jiang Y;Karpinchyk V;Koenig M;Kong C;Landers T;Le C;Liu J;McBride CE;Morenzoni M;Morey RE;Mutch K;Perazich H;Perry K;Peters BA;Peterson J;Pethiyagoda CL;Pothuraju K;Richter C;Rosenbaum AM;Roy S;Shafto J;Sharanhovich U;Shannon KW;Sheppy CG;Sun M;Thakuria JV;Tran A;Vu D;Zaranek AW;Wu X;Drmanac S;Oliphant AR;Banyai WC;Martin B;Ballinger DG;Church GM;Reid CA;; |
| Journal | Science (New York, N.Y.) |
| Year | 2010 |
| DOI | DOI not found |
| URL | |
| Keywords |
software
databases
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
nanotechnology
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
male
N.I.H.
Extramural
Sequence Analysis
genome
Base Sequence
Genotype
Polymorphism
DNA / methods*
computational biology
nucleic acid
costs and cost analysis
nucleic acid amplification techniques
single nucleotide
human*
dna / economics
dna / standards
haplotypes
dna / genetics
human genome project
pmid:19892942
doi:10.1126/science.1181498
radoje drmanac
andrew b sparks
clifford a reid
dna / chemistry*
genomic library
microarray analysis*
nanostructures
dna / instrumentation
|
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