Effects of sofosbuvir-based treatment, with and without interferon, on outcome and productivity of patients with chronic hepatitis C

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ID: 271821
2014
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Abstract
On the basis of an analysis of 2 large clinical trials (FUSION and NEUTRINO), patient outcome and productivity are more negatively affected by the inclusion of pegylated interferon in treatment than by interferon-free regimens. Patients with sustained virologic responses 12 weeks after treatment had ā€¦
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Authors Younossi ZM;Stepanova M;Henry L;Gane E;Jacobson IM;Lawitz E;Nelson D;Gerber L;Nader F;Hunt S;;
Journal clinical gastroenterology and hepatology : the official clinical practice journal of the american gastroenterological association
Year 2014
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/24316172
Keywords
hepatitis c National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine treatment outcome research support non-u.s. gov't Surveys and Questionnaires randomized controlled trials as topic efficiency Genotype antiviral agents / therapeutic use* ribavirin / therapeutic use hepacivirus / isolation & purification chronic / drug therapy* quality of life hepacivirus / classification hepacivirus / genetics maria stepanova zobair m younossi sharon hunt pmid:24316172 doi:10.1016/j.cgh.2013.11.032 interferons / therapeutic use* sofosbuvir uridine monophosphate / analogs & derivatives* uridine monophosphate / therapeutic use

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