Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5

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ID: 271735
2004
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Abstract
Women with polycystic ovary syndrome (PCOS) have high circulating androgens, thought to originate from ovaries and adrenals, and frequently suffer from the metabolic syndrome including obesity. However, serum androgens are positively associated with body mass index (BMI) not only in PCOS, but also i ā€¦
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Authors Quinkler M;Sinha B;Tomlinson JW;Bujalska IJ;Stewart PM;Arlt W;;
Journal the journal of endocrinology
Year 2004
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/15531721
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't adult female middle aged Cells Cultured body mass index Adipose Tissue / metabolism* cell differentiation cell proliferation obesity / metabolism* Androstenedione / metabolism testosterone / biosynthesis pmid:15531721 doi:10.1677/joe.1.05762 marcus quinkler binayak sinha wiebke arlt 17-hydroxysteroid dehydrogenases / metabolism* androgens / biosynthesis* isoenzymes / metabolism*

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