Spread of an Inactive Form of Caspase-12 in Humans Is Due to Recent Positive Selection
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2006
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The human caspase-12 gene is polymorphic for the presence or absence of a stop codon, which results in the occurrence of both active (ancestral) and inactive (derived) forms of the gene in the population. It has been shown elsewhere that carriers of the ...
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Authors | Yali Xue, Allan Daly, Bryndis Yngvadottir, Mengning Liu, Graham Coop, Yuseob Kim, Pardis Sabeti, Yuan Chen, Jim Stalker, Elizabeth Huckle, John Burton, Steven Leonard, Jane Rogers, Chris Tyler-Smith;Yali Xue;Allan Daly;Bryndis Yngvadottir;Mengning Liu;Graham Coop;Yuseob Kim;Pardis Sabeti;Yuan Chen;Jim Stalker;Elizabeth Huckle;John Burton;Steven Leonard;Jane Rogers;Chris Tyler-Smith; |
Journal | American journal of human genetics |
Year | 2006 |
DOI | 10.1086/503116 |
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