Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects

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ID: 271263
1996
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Exercise increases insulin sensitivity in both normal subjects and the insulin-resistant offspring of diabetic parents because of a twofold increase in insulin-stimulated glycogen synthesis in muscle, due to an increase in insulin-stimulated glucose transport-phosphorylation.
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Authors Perseghin G;Price TB;Petersen KF;Roden M;Cline GW;Gerow K;Rothman DL;Shulman GI;;
Journal The New England journal of medicine
Year 1996
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8857019
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't adult female male P.H.S. Glucose / metabolism* Active diabetes mellitus insulin resistance / physiology* insulin / metabolism insulin secretion exercise / physiology phosphorylation physical fitness / physiology* muscle biological transport type 2 / genetics glucose clamp technique skeletal / metabolism* pmid:8857019 doi:10.1056/nejm199610313351804 g perseghin t b price g i shulman glucose-6-phosphate / metabolism glycogen / biosynthesis*

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