Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia
Clicks: 177
ID: 270551
2008
Classic tissue recombination and in vitro lineage tracing studies suggest that condensed metanephric mesenchyme (MM) gives rise to nephronic epithelium of the adult kidney. However, these studies do not distinguish between cap mesenchyme and pre-tubular aggregates comprising the condensed MM, nor do …
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s2008developmentalfate
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Authors | Boyle S;Misfeldt A;Chandler KJ;Deal KK;Southard-Smith EM;Mortlock DP;Baldwin HS;de Caestecker M;; |
Journal | Developmental biology |
Year | 2008 |
DOI | DOI not found |
URL | |
Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
N.I.H.
Extramural
nuclear proteins / metabolism
transgenic
nuclear proteins / genetics
stem cells / cytology*
trans-activators / metabolism
trans-activators / genetics
pmid:18061157
pmc2699557
doi:10.1016/j.ydbio.2007.10.014
scott boyle
andrew misfeldt
mark de caestecker
apoptosis regulatory proteins
cell lineage*
epithelial cells / cytology*
kidney / cytology*
kidney / embryology*
mesoderm / cytology*
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