A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1β Release in Response to a Pathogenic Fungus

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ID: 270413
2018
The fungal pathogen P brasiliensis activates caspase-8 downstream of dectin-1 recognition leading to ASC oligomerization, caspase-1 activation, and IL-1β proces
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Authors Ketelut-Carneiro, Natália;Ghosh, Sreya;Levitz, Stuart M;Fitzgerald, Katherine A;da Silva, João Santana;
Journal The Journal of infectious diseases
Year 2018
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