Repair of large segmental bone defects: BMP-2 gene activated muscle grafts vs. autologous bone grafting
Clicks: 195
ID: 270369
2013
Common cell based strategies for the treatment of osseous defects require the isolation and expansion of autologous cells. Since this makes such approaches time-consuming and expensive, we developed a novel expedited technology creating gene activated muscle grafts. We have previously shown that large segmental bone defects in rats can be regenerated by implantation of muscle tissue fragments activated by BMP-2 gene transfer.
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müller2013bmcrepair
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| Authors | Oliver B Betz,Volker M Betz,Christian Schröder,Rainer Penzkofer,Michael Göttlinger,Susanne Mayer-Wagner,Peter Augat,Volkmar Jansson,Peter E Müller;Oliver B Betz;Volker M Betz;Christian Schröder;Rainer Penzkofer;Michael Göttlinger;Susanne Mayer-Wagner;Peter Augat;Volkmar Jansson;Peter E Müller; |
| Journal | bmc biotechnology |
| Year | 2013 |
| DOI | 10.1186/1472-6750-13-65 |
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