N-methyl-D-aspartate receptor signaling results in Aurora kinase-catalyzed CPEB phosphorylation and alpha CaMKII mRNA polyadenylation at synapses

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2002
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Abstract
Activity-dependent local translation of dendritic mRNAs is one process that underlies synaptic plasticity. Here, we demonstrate that several of the factors known to control polyadenylation-induced translation in early vertebrate development [cytoplasmic polyadenylation element-binding protein (CPEB) ā€¦
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Authors Huang YS;Jung MY;Sarkissian M;Richter JD;;
Journal the embo journal
Year 2002
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/11980711
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE RNA animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't female amino acid sequence P.H.S. Rats Receptors Transcription Factors / metabolism* Molecular Sequence Data messenger / metabolism phosphorylation signal transduction / physiology* oocytes / physiology xenopus proteins* hippocampus / physiology aurora kinases calcium-calmodulin-dependent protein kinase type 2 pmid:11980711 pmc125376 doi:10.1093/emboj/21.9.2139 yi-shuian huang mi-young jung joel d richter calcium-calmodulin-dependent protein kinases / genetics* polyadenylation / physiology protein-serine-threonine kinases / physiology* rna-binding proteins / metabolism* n-methyl-d-aspartate / physiology* synapses / physiology* xenopus / physiology mrna cleavage and polyadenylation factors*

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