C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation
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ID: 269571
2021
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Abstract
Recurrent C11orf95-RELA fusions (RELA[FUS] ) are the hallmark of supratentorial ependymomas. The presence of RELA as the fusion partner indicates a close association of aberrant NF-κB activity with tumorigenesis. However, the oncogenic role of ...| Reference Key |
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| Authors | Tatsuya Ozawa, Syuzo Kaneko, Frank Szulzewsky, Zhiwei Qiao, Mutsumi Takadera, Yoshitaka Narita, Tadashi Kondo, Eric C. Holland, Ryuji Hamamoto, Koichi Ichimura;Tatsuya Ozawa;Syuzo Kaneko;Frank Szulzewsky;Zhiwei Qiao;Mutsumi Takadera;Yoshitaka Narita;Tadashi Kondo;Eric C. Holland;Ryuji Hamamoto;Koichi Ichimura; |
| Journal | acta neuropathologica communications |
| Year | 2021 |
| DOI | 10.1186/s40478-021-01135-4 |
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