Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle

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ID: 269176
2006
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Abstract
Resistance exercise is a potent stimulator of muscle protein synthesis and muscle cell growth, with the increase in protein synthesis being detected within 2-3 h post-exercise and remaining elevated for up to 48 h. However, during exercise, muscle protein synthesis is inhibited. An increase in AMP-a ā€¦
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Authors Dreyer HC;Fujita S;Cadenas JG;Chinkes DL;Volpi E;Rasmussen BB;;
Journal the journal of physiology
Year 2006
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16873412
Keywords
biopsy National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't non-p.h.s. adult female male N.I.H. Extramural exercise / physiology* hydrogen-ion concentration phosphorylation amino acids / metabolism muscle protein-serine-threonine kinases / metabolism* phosphoproteins / metabolism* adaptor proteins lactates / metabolism protein-serine-threonine kinases / genetics glucose / pharmacokinetics protein kinases / metabolism pmid:16873412 pmc1890364 doi:10.1113/jphysiol.2006.113175 hans c dreyer satoshi fujita blake b rasmussen amp-activated protein kinases signal transducing / metabolism* cell cycle proteins multienzyme complexes / genetics multienzyme complexes / metabolism* muscle proteins / metabolism* skeletal / blood supply skeletal / metabolism* skeletal / pathology regional blood flow / physiology tor serine-threonine kinases weight lifting / physiology

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