Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and Agouti-related protein mRNA levels and body weight in rats

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ID: 268891
2001
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Abstract
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHS-R), was originally purified from the rat stomach. Like the synthetic growth hormone secretagogues (GHSs), ghrelin specifically releases growth hormone (GH) after intravenous administration. Also consistent with the centr ā€¦
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Authors Kamegai J;Tamura H;Shimizu T;Ishii S;Sugihara H;Wakabayashi I;;
Journal Diabetes
Year 2001
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/11679419
Keywords
injections National Center for Biotechnology Information NCBI NLM MEDLINE RNA animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't male Drug Administration Schedule Rats Sprague-Dawley proteins / genetics* messenger / metabolism* hypothalamus / metabolism* gene expression / drug effects pmid:11679419 doi:10.2337/diabetes.50.11.2438 j kamegai h tamura i wakabayashi agouti-related protein body weight / drug effects* eating / drug effects ghrelin hypothalamus / drug effects intraventricular intercellular signaling peptides and proteins neuropeptide y / metabolism* peptide hormones* peptides / administration & dosage* peptides / pharmacology

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