SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

Clicks: 297
ID: 266238
1993
Sterol regulatory element 1 (SRE-1), a decamer (5'-ATC-ACCCCAC-3') flanking the low density lipoprotein (LDL) receptor gene, activates transcription in sterol-depleted cells and is silenced by sterols. We report the cDNA cloning of human SREBP-1, a protein that binds SRE-1, activates transcription, …
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Authors Yokoyama C;Wang X;Briggs MR;Admon A;Wu J;Hua X;Goldstein JL;Brown MS;;
Journal Cell
Year 1993
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