The advanced glycation end product pentosidine correlates to IL-6 and other relevant inflammatory markers in rheumatoid arthritis
Clicks: 392
ID: 266124
2005
The binding of AGE on cell receptors induces activation of nuclear factor kappa B, resulting in enhanced synthesis of proinflammatory cytokines. Moreover, AGE generation may also lead to the formation of new, immunologically relevant epitopes at synovial proteins. Both mechanisms could contribute to …
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Authors | Hein GE;Köhler M;Oelzner P;Stein G;Franke S;; |
Journal | Rheumatology international |
Year | 2005 |
DOI | DOI not found |
URL | |
Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
female
male
middle aged
Receptors
radiography
biomarkers / blood*
c-reactive protein / analysis
arthritis
rheumatoid / diagnostic imaging
blood sedimentation
pmid:15580352
doi:10.1007/s00296-004-0518-1
gert e hein
markus köhler
sybille franke
arginine / analogs & derivatives*
arginine / blood
rheumatoid / blood*
glycation end products
advanced
interleukin-6 / blood*
lysine / analogs & derivatives*
lysine / blood
cytokine / blood
rheumatoid factor / blood
rheumatology / methods*
synovial fluid / chemistry
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