ATP responsive DNA nanogels grown on biocompatible branches for anticancer drug delivery.

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2019
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Abstract
We developed biocompatible ATP responsive DNA nanogels, by grafting DNA strands on carboxymethyl chitosan polymer chains, and then hybridizing with ATP aptamers to form core-shell nanogels. The DNA duplex structure could embed DOX in the G-C sequences, and realize simultaneous sol-gel transition and DOX release when suffering enrich ATP in tumor cells.
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zhao2019atpsoft Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zhao, Meihui;Zhang, Yu;Yuan, Shirui;Xu, Xiang;Wu, Ziheng;Wu, Zhenghong;Qi, Xiaole;
Journal Soft matter
Year 2019
DOI 10.1039/c9sm00480g
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