Clonal dominance patterns of CD8 T cells in relation to disease progression in HIV-infected children

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ID: 261927
1999
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Abstract
CD8 T cells are important mediators of cellular immune responses as evidenced by clonal expansions in the CD8 TCR V beta repertoire during primary HIV infection in adults. This study investigated the CD8 TCR V beta repertoire by complementarity-determining region 3 length analysis using multiplex PC ā€¦
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Authors Than S;Kharbanda M;Chitnis V;Bakshi S;Gregersen PK;Pahwa S;;
Journal Journal of immunology (Baltimore, Md. : 1950)
Year 1999
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/10092830
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't adolescent Child Infant Comparative Study P.H.S. preschool Cells Cultured polymerase chain reaction Receptors disease progression cd4 lymphocyte count hiv infections / immunology* hiv infections / blood lymphocyte activation cd8-positive t-lymphocytes / immunology* hiv infections / metabolism s pahwa pmid:10092830 s than m kharbanda cd8-positive t-lymphocytes / metabolism* clone cells / immunology clone cells / metabolism fetal blood / metabolism immunoglobulin variable region / genetics antigen t-cell alpha-beta / biosynthesis alpha-beta / genetics

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