Evaluation of human immunodeficiency virus (HIV) type 1 RNA levels in cerebrospinal fluid and viral resistance to zidovudine in children with HIV encephalopathy

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ID: 260838
1996
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Abstract
The amount of human immunodeficiency virus (HIV) type 1 RNA and the presence of a codon 215 mutation indicative of zidovudine resistance were evaluated in cerebrospinal fluid (CSF) and plasma obtained from HIV-1-infected children. The level of HIV-1 RNA in CSF was highest in children with severe enc ā€¦
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Authors Sei S;Stewart SK;Farley M;Mueller BU;Lane JR;Robb ML;Brouwers P;Pizzo PA;;
Journal The Journal of infectious diseases
Year 1996
DOI DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8940209
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE RNA humans pubmed abstract nih national institutes of health national library of medicine Child Infant preschool Genes polymerase chain reaction follow-up studies drug resistance viral / analysis* p a pizzo microbial / genetics* disease progression cd4 lymphocyte count hiv-1 / growth & development* anti-hiv agents / therapeutic use* hiv infections / drug therapy* hiv infections / blood hiv infections / virology* zidovudine / therapeutic use* point mutation hiv core protein p24 / analysis pmid:8940209 doi:10.1093/infdis/174.6.1200 s sei s k stewart aids dementia complex / blood aids dementia complex / cerebrospinal fluid aids dementia complex / drug therapy* aids dementia complex / virology* pol hiv infections / cerebrospinal fluid hiv-1 / genetics* hiv-1 / pathogenicity

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