restrictive extraocular myopathy: a presenting feature of acromegaly

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2011
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Abstract
A 45-year-old man presented with binocular diplopia in primary gaze for 1 year. Orthoptic evaluation showed 10-prism diopter right eye hypotropia and 6-prism diopter right eye esotropia. The elevation and abduction of the right eye were mechanically restricted. This was associated with systemic features suggestive of acromegaly. Magnetic resonance imaging (MRI) of the brain demonstrated a pituitary macroadenoma. An elevated serum insulin-like growth factor I level and the failure of growth hormone suppression after an oral glucose load biochemically confirmed the diagnosis of acromegaly. Computed tomography (CT) of the orbit demonstrated bilateral symmetrical enlargement of the medial rectus and inferior rectus muscle bellies. All tests regarding Graves-Basedow disease were negative. Although rare, diplopia due to a restrictive extraocular myopathy could be the presenting symptom of acromegaly.
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Authors ;Steven Heireman;Christophe Delaey;Ilse Claerhout;Christian E Decock
Journal Bioinformatics
Year 2011
DOI 10.4103/0301-4738.86330
URL
http://www.ijo.in/article.asp?issn=0301-4738;year=2011;volume=59;issue=6;spage=517;epage=519;aulast=Heireman
Keywords
Susceptibility Risk factors Screening Microbiology prism neuroimaging acromegaly survey refractive errors risk factor diplopia myopia glaucoma cataract treatment outcome axial length anterior chamber depth spectral domain optical coherence tomography minimum inhibitory concentration hypermetropia anthrax pituitary adenoma suprasellar tumor retinoblastoma prognostic factors retinopathy of prematurity progeria cerebrospinal fluid leakage macular hole pars plana vitrectomy presbyopia visual impairments esotropia

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