n-acetyltransferase 2 slow acetylator genotype associated with adverse effects of sulfasalazine in the treatment of inflammatory bowel disease

Clicks: 146
ID: 256244
2007
AIM: N-acetyltransferase 2 (NAT2) is an important enzyme catalyzing N-acetylation of sulfasalazine (SASP). The aim of the present study was to investigate associations of the genotypes of NAT2 with inflammatory bowel disease (IBD), and with adverse effects of SASP, which is used as the first-line treatment of IBD.
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Authors ;Min Chen;Bing Xia;Bixiao Chen;Qiusha Guo;Jin Li;Mei Ye;Zhengguo Hu
Journal indian journal of pharmacology
Year 2007
DOI 10.1155/2007/976804
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