fatores dietéticos e câncer oral: estudo caso-controle na região metropolitana de são paulo, brasil dietary factors and oral cancer: a case-control study in greater metropolitan são paulo, brazil
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ID: 232576
2007
Neste estudo, investigou-se os fatores dietéticos associados com o câncer oral, em um estudo tipo caso-controle de base hospitalar no Município de São Paulo, Brasil, entre 1998 e 2002. Participaram 835 indivíduos, sendo 366 casos incidentes de câncer de cavidade oral ou faringe e 469 controles. Os dados de consumo alimentar foram obtidos por um Questionário de Freqüência Alimentar (QFA). Os valores de odds ratio (OR) e intervalos com 95% de confiança (IC95%) foram estimados por regressão logística não condicional, ajustada por potenciais fatores de confusão. Verificaram-se associações inversas entre o câncer oral e o consumo mais elevado de feijão, OR = 0,37 (IC95%: 0,22-0,64), vegetais crus, OR = 0,51 (IC95%: 0,29-0,93) e para o tercil intermediário de arroz e massas, OR = 0,56 (IC95%: 0,38-0,83). Associações diretas foram observadas para o mais elevado consumo de ovos, OR = 1,84 (IC95%: 1,23-2,75), batata, OR = 2,22 (IC95%: 1,53-3,25) e leite, OR= 1,80 (IC95%: 1,09-2,98). Alimentos básicos da dieta do brasileiro, como arroz e feijão, emergiram como fatores de proteção para o câncer oral, independente de outros fatores de risco.
Dietary factors associated with oral cancer were investigated in a case-control hospital-based study in the city of São Paulo, Brazil, from 1998 to 2002. A total of 835 subjects, 366 with histologically confirmed incident cases of oral-cavity or pharyngeal cancer and 469 controls participated in the study. Dietary data were collected with a food frequency questionnaire (FFQ). Odds ratios (OR) and 95% confidence intervals (95%CI) were obtained from unconditional logistic regression, adjusted for potential confounders. Inverse associations with risk of oral cancer were found for the highest intake of beans, OR = 0.37 (95%CI: 0.22-0.64), raw vegetables, OR = 0.51 (95%CI: 0.29-0.93) and the intermediate tertile of rice and pasta intake, OR = 0.56 (95%CI: 0.38-0.83). Positive associations were observed for the highest intake of eggs, OR = 1.84 (95%CI: 1.23-2.75), potatoes, OR = 2.22 (95%CI: 1.53-3.25), and milk, OR= 1.80 (95%CI: 1.09-2.98). Some traditional Brazilian foods like rice and beans emerged as protective factors against oral cancer, independently of other risk factors.
Dietary factors associated with oral cancer were investigated in a case-control hospital-based study in the city of São Paulo, Brazil, from 1998 to 2002. A total of 835 subjects, 366 with histologically confirmed incident cases of oral-cavity or pharyngeal cancer and 469 controls participated in the study. Dietary data were collected with a food frequency questionnaire (FFQ). Odds ratios (OR) and 95% confidence intervals (95%CI) were obtained from unconditional logistic regression, adjusted for potential confounders. Inverse associations with risk of oral cancer were found for the highest intake of beans, OR = 0.37 (95%CI: 0.22-0.64), raw vegetables, OR = 0.51 (95%CI: 0.29-0.93) and the intermediate tertile of rice and pasta intake, OR = 0.56 (95%CI: 0.38-0.83). Positive associations were observed for the highest intake of eggs, OR = 1.84 (95%CI: 1.23-2.75), potatoes, OR = 2.22 (95%CI: 1.53-3.25), and milk, OR= 1.80 (95%CI: 1.09-2.98). Some traditional Brazilian foods like rice and beans emerged as protective factors against oral cancer, independently of other risk factors.
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Authors | ;Dirce Maria Lobo Marchioni;Regina Mara Fisberg;José Francisco de Góis Filho;Luiz Paulo Kowalski;Marcos Brasilino de Carvalho;Márcio Abrahão;Maria do Rosario Dias de Oliveira Latorre;José Eluf Neto;Victor Wünsch-Filho |
Journal | iberian conference on information systems and technologies, cisti |
Year | 2007 |
DOI | 10.1590/S0102-311X2007000300014 |
URL | |
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