cholecystokinin-like peptide (dsk) in drosophila, not only for satiety signaling
Clicks: 182
ID: 206195
2014
Cholecystokinin (CCK) signaling appears well conserved over evolution. In Drosophila the CCK-like sulfakinins (DSKs) regulate aspects of gut function, satiety and food ingestion, hyperactivity and aggression, as well as escape-related locomotion and synaptic plasticity during NMJ development. Activity in the DSK-producing neurons is regulated by octopamine. We discuss mechanisms behind CCK function in satiety, aggression and locomotion in some detail and highlight similarities to mammalian CCK signaling.
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nssel2014frontierscholecystokinin-like
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Authors | ;Dick R Nässel;Michael J Williams |
Journal | aip advances |
Year | 2014 |
DOI | 10.3389/fendo.2014.00219 |
URL | |
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