acute monoblastic leukemia with abnormal eosinophils and inversion (16): a rare entity

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2016
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Abstract
Acute myeloid leukemia (AML) is a malignant hematopoietic stem cell disorder which is sub-classified based on bone marrow morphology and the presence of specific genetic abnormalities. One such cytogenetic abnormality is the pericentric inversion (inv) of chromosome 16 which is typically seen in AML M4 with eosinophilia and is associated with a favorable prognosis. We report the inv (16) in a young woman with AML M5 and abnormal eosinophils. This is a rare entity with only about 20 cases being reported till date.
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Authors ;Kiruthiga Kala Gnanasekaran;Mary P Chacko;Marie Therese Manipadam;M S Bindra;Biju George;Vivi M Srivastava
Journal journal of materials processing technology
Year 2016
DOI 10.4103/0377-4929.174829
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