perfluoroalkanesulfonamide organocatalysts for asymmetric conjugate additions of branched aldehydes to vinyl sulfones

Clicks: 134
ID: 201521
2013
Asymmetric conjugate additions of branched aldehydes to vinyl sulfones promoted by sulfonamide organocatalyst 6 or 7 have been developed, allowing facile synthesis of the corresponding adducts with all-carbon quaternary stereocenters in excellent yields with up to 95% ee.
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Authors ;Kosuke Nakashima;Miho Murahashi;Hiroki Yuasa;Mariko Ina;Norihiro Tada;Akichika Itoh;Shin-ichi Hirashima;Yuji Koseki;Tsuyoshi Miura
Journal Journal of ethnopharmacology
Year 2013
DOI 10.3390/molecules181214529
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