histamine mediates the pro-inflammatory effect of latex of calotropis procera in rats

Clicks: 139
ID: 183893
2003
Introduction: Calotropis procera is known to produce contact dermatitis and the latex of this plant produces intense inflammation when injected locally. However, the precise mode of its pro-inflammatory effect is not known. In present study we have pharmacologically characterized the inflammation induced by latex of C. procera in a rat paw edema model and determined the role of histamine in latex-induced inflammation.
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Authors ;Yatin M. Shivkar;Vijay L. Kumar
Journal polyhedron
Year 2003
DOI 10.1080/096293503310001619708
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