Anti-inflammatory Dendranacetylene A, a new polyacetylene glucoside from the flower of Ramat.
Clicks: 181
ID: 171932
2020
A new polyacetylene glucoside, Dendranacetylene A (1), and a known compound 8E-decaene-4,6-diyn-1-O--d-glucopyranosyl-(1"→2")--d-glucopyranoside (2) were isolated from the flowers of (Ramat.) kitam. The chemical structures of these compounds were elucidated by NMR and HR-ESI-MS analysis, and comparing these results with data reported in literatures. Additionally, the anti-inflammatory effects of compounds 1 and 2 were evaluated on RAW264.7 murine macrophage cells induced by lipopolysaccharide (LPS). The two compounds significantly inhibited the NO production in LPS-induced RAW 264.7 murine macrophage cells and exhibited anti-inflammatory effects.
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| Authors | Li, Meng;Zeng, Mengnan;Zhang, Jingke;Shi, Jingya;Lv, Jinjin;Tang, Yingying;Zheng, Xiao-Ke;Feng, Wei-Sheng; |
| Journal | Natural product research |
| Year | 2020 |
| DOI | 10.1080/14786419.2020.1825425 |
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