investigation of fatty acid ketohydrazone modified liposome’s properties as a drug carrier

Clicks: 128
ID: 162004
2015
pH-responsive liposomes were prepared by modifying the liposome with acid-cleaving amphiphiles. Palmitic ketohydrazone (P-KH) or stearic ketohydrazone (S-KH), composed of hydrophilic sugar headgroup and hydrophobic acyl chain, was used as a modifier of the DMPC liposome. Because the ketohydrazone group of P-KH or S-KH was cleaved at low pH conditions (
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Authors ;Keita Hayashi;Madoka Kiriishi;Keishi Suga;Yukihiro Okamoto;Hiroshi Umakoshi
Journal linux dev center, downloaded from http://www linuxdevcenter com/lpt/a/1636
Year 2015
DOI 10.1155/2015/481670
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