fanconi anemia and vaginal squamous cell carcinoma

Clicks: 164
ID: 158582
2012
Fanconi Anemia (FA) is an autosomal recessive disease characterized by chromosome instability, cellular hypersensitivity to DNA cross-linking agents, and increased predisposition to malignancies. We describe here a 28 year-old female with FA and vaginal squamous cell carcinoma treated by radiation therapy alone. The patient developed arm phlebitis, pulmonary fungal infection, and severe rectal bleeding, followed by hypocalcaemia, hypokalemia, vaginal bacterial and fungal infection, with subsequent leg and arm phlebitis, perineal abscess, and sepsis. The patient died 12 weeks later.
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Authors ;Jesus Paula Carvalho;Edmund Chada Baracat;Maria Del Pilar Esteves Diz;Heloisa de Andrade Carvalho;Filomena Marino de Carvalho;Marcela Cavalcante de Andrade Silva;Altamiro Ribeiro Dias Jr.
Journal revista de urbanismo
Year 2012
DOI 10.4081/rt.2012.e4
URL
http://www.pagepress.org/journals/index.php/rt/article/view/2960
Keywords
fanconi anemia Oncology radiation therapy squamous cell carcinoma including cancer and carcinogens tumors

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